The interrelation between chronic stress and MS has always been known, but the biological foundation for this phenomenon has not yet been proven. A case-study of five patients, both diagnosed with MS and PTSD, attempts to demonstrate various dimensions of interrelation between these two diseases. The article, published in Pyschiatria Danubina, points out the problems and possible complications doctors might encounter during the treatment of a patient with MS who is suffering from chronic stress. The findings show the need for a multidisciplinary approach in the treatment of patients with chronic PTSD and co-morbid MS, which will optimize treatment and result in more cost-effective care. Appropriate identification and optimal pharmacological interventions for both disorders might modify further chronicity of these disorders and thus achieve better outcome. This study was conducted at the Clinic for Psychological Medicine at the University Hospital Center Zagreb, Croatia. (Available from:http://www.pubmed.gov, PMID: 18376335)

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